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AMPICILLIN SODIUM SALT

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제품명 AMPICILLIN SODIUM SALT
제조사 MP Biomedicals
제품번호 0219014825
사이즈 25g

 

02190148 MP BIOMEDICALS

AMPICILLIN SODIUM SALT

·        Download MSDS (PDF)

Synonyms D(-)-α-Aminobenzylpenicillin sodium salt, 6-[D(-)-a-Aminophenylacetamido]penicillanic acid

 

·        CAS Number 69-52-3

·        Molecular Formula C16H18N3NaO4S

·        Molecular Weight 371.39

·        Beilstein Registry Number 4119211

·        EC Number 200-708-1

·        MDL Number MFCD00064313

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Applications

Used to select for ampicillin resistance in mutated and transformed cells.

 

Product Description

Ampicillin is a semi-synthetic derivative of penicillin, active as a broad-spectrum antibiotic. It is inactivated by beta-lactamases and for this reason a beta-lactamase inhibitor should be considered when using ampicillin. Against gram-positive bacteria, ampicillin has a similar mode of action as benzylpenicillin; against gram-negative bacteria, it has a similar mode of action as chloramphenicol and tetracyclines. In E. coli it inhibits cell wall synthesis.

 

Biochem/physiol Actions

A β-lactam antibiotic with an amino group side chain attached to the penicillin structure. Penicillin derivative that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing Escherichia coli. Mode of resistance: Cleavage of β-lactam ring of ampicillin by β-lactamase. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria

 

 

 

 

 

 

 


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