상품상세 정보
Halohydrin dehalogenase of ANGEL
| 제품명 | Halohydrin dehalogenase of ANGEL |
|---|---|
| 제조사 | ANGEL YEAST |
| 제품번호 | Halohydrin dehalogenase of ANGEL |
| 제품설명 | Halohydrin dehalogenase of ANGEL is a newly developed technical-grade enzyme product by our company. The enzyme is of great value for the production of optically pure aliphatic and aromatic epoxides, halohydrins, and β-substituted alcohols, all of which are valuable building blocks in pharmaceutical synthesis. The enzyme has already been successfully applied in the synthesis of A5, an intermediate of Atorvastatin Calcium side chain. |
Catalytic promiscuity of halohydrin dehalogenase
The enzyme enantioselectively catalyzes not only the dehalogenation of halohydris, but also epoxides-ring opening reaction by accepting a wide range of nucleophiles N3-, NO2-, CN-, OCN-, SCN- in addition to haide ions, to produce a series of optically pure β-substituted alcohols.
Application
1、Application in the synthesis of the intermediate of statin
2、Application in the synthesis of the anti-inflammatory intermediate
3、Application in the degradation of the pesticide
4、Other applications
Type of the halohydrin dehalogenase
Type：Dehalogenase Hhe-C120(liquid)
Dehalogenase Hhe-C1000(solid)
Packing Specifications：25kg/ barrel(liquid/solid)
200kg/barrel(liquid/solid)